Easy Chicken Alfredo Lasagna

Category: Everyday Mains Made Simple

This dish features tender chicken tenders cooked and chopped, nestled between layers of lasagna sheets and a creamy spinach Alfredo sauce. Mozzarella and Parmesan cheeses add richness, while aromatic butter, garlic, and onion build a flavorful base. The assembled layers bake covered for 40 minutes, then uncovered to develop a golden top. After resting, it’s garnished and served warm, offering a comforting blend of textures and flavors in every bite.

Breanna smiling at the camera.
Created By Breanna
Last updated on Fri, 09 Jan 2026 15:57:01 GMT
A plate of chicken Alfredo lasagna. Save
A plate of chicken Alfredo lasagna. | foodiffy.com

This chicken Alfredo lasagna has become my favorite for weekend dinners when I want something comforting but still impressive. It layers tender chicken and creamy spinach Alfredo for a rich and satisfying meal that feels special without fuss.

It was one of those recipes I cobbled together after a long day and surprised everyone with how cozy and creamy it turned out

Ingredients

  • Chicken tenders: provide juicy lean protein that cooks quickly and stays tender
  • Lasagna sheets: create the perfect structure for layers make sure to pick quality sheets that won't overcook or stick
  • Mozzarella: adds melty gooey goodness and a mild flavor to balance the rich sauce
  • Butter: builds a rich base for cooking onions and garlic adding depth
  • Onion and garlic: bring aromatics that form the savory foundation for the sauce
  • Milk and cream: form the creamy Alfredo sauce choose fresh dairy for best texture and flavor
  • Parmesan cheese: sharpens the sauce with its nutty umami punch use a good aged cheese
  • Fresh spinach: adds a vibrant green color and mild earthiness aiming for bright fresh leaves over wilted or frozen
  • Spices: enhance the flavor profile and can be adjusted to taste but I think a touch of nutmeg really brightens the sauce

Instructions

Build The Chicken:
Cook chicken tenders gently in a skillet until just cooked through then chop into bite-sized pieces. Keeping the chicken moist at this stage locks in flavor and ensures it blends well in the layers.
Prepare The Spinach Alfredo Sauce:
In the same skillet melt butter over medium low heat then add finely chopped onion and garlic. Cook slowly for about ten minutes until soft and fragrant. This slow cook is key to unlocking sweetness and depth before stirring in milk and cream. Bring gently to a simmer then add grated Parmesan cheese and a pinch of nutmeg. Stir constantly so the sauce thickens smoothly without burning. Finally fold in fresh spinach leaves until they wilt and blend fully into the sauce.
Assemble The Lasagna:
In your baking dish start with a thin layer of sauce to prevent sticking. Lay down lasagna sheets evenly then spread a generous layer of spinach Alfredo followed by chopped chicken and a sprinkle of shredded mozzarella. Repeat these layers finishing off with a good covering of sauce and more mozzarella on top.
Bake Until Perfect:
Cover the dish tightly with foil and bake at moderate heat for about forty minutes to let everything meld and stay moist. Remove the foil in the last ten minutes so the cheese melts fully and develops a golden crust.
Rest And Serve:
Let the lasagna rest for ten to fifteen minutes after baking. This allows the layers to set and makes serving neater. Garnish with a few fresh spinach leaves or extra Parmesan if desired and enjoy.
A pan of chicken Alfredo lasagna.
A pan of chicken Alfredo lasagna. | foodiffy.com

The fresh spinach is my favorite part it brightens the creamy sauce beautifully and adds a healthy pop of color. This recipe always brings back memories of cozy family dinners when everyone reaches eagerly for seconds

Storage tips

Store leftovers in an airtight container and keep in the fridge for up to four days. Reheat gently covered in the oven or microwave to preserve creaminess without drying out.

Ingredient swaps

If fresh spinach is unavailable use frozen but squeeze out as much moisture as possible. For a lighter twist swap half the cream with milk or add some ricotta for extra creaminess. Any mild melting cheese like provolone or fontina works well instead of mozzarella.

Serving ideas

Pair with a crisp green salad tossed with lemon vinaigrette to cut through the richness. Garlic bread or warm focaccia also complement this dish perfectly. For a heartier side try roasted vegetables or a simple tomato salad.

A pan of chicken Alfredo lasagna.
A pan of chicken Alfredo lasagna. | foodiffy.com

This lasagna combines creamy Alfredo with tender chicken and fresh spinach for a comforting yet impressive meal perfect for weekend dinners.

Frequently Asked Recipe Questions

→ What type of chicken works best?

Chicken tenders or boneless breast pieces provide tender, juicy results and cook evenly within the layers.

→ Can I use fresh spinach instead of frozen?

Fresh spinach works well; sauté it briefly to remove excess moisture before mixing into the Alfredo sauce.

→ How do I prevent the lasagna from drying out?

Covering the dish during most of the bake traps moisture, and the creamy sauce helps keep it rich and moist.

→ Is it necessary to rest lasagna after baking?

Allowing the lasagna to rest for a few minutes helps the layers set for cleaner slices and enhanced flavors.

→ What spices complement this dish?

Classic Italian herbs like oregano, basil, and a pinch of nutmeg enhance the depth of the Alfredo and chicken flavors.

Easy Chicken Alfredo Lasagna

Layers of tender chicken, creamy Alfredo, spinach, and mozzarella combine for a rich, satisfying baked dish.

Preparation Time
30 mins
Time to Cook
70 mins
Overall Time
100 mins
Created By: Breanna

Type of Recipe: Lunch & Dinner

Cooking Difficulty: Suitable for Beginners

Cultural Origin: Italian

Portion Size: 6 Number of Servings (One 22x30 cm casserole)

Dietary Options: ~

Ingredients Required

→ Protein

01 300 grams chicken tenders

→ Pasta

02 250 grams dried lasagna sheets

→ Cheese

03 150 grams shredded mozzarella
04 50 grams grated Parmesan cheese

→ Dairy

05 30 grams unsalted butter
06 250 milliliters whole milk
07 100 milliliters heavy cream

→ Vegetables and Aromatics

08 1 medium onion, finely chopped
09 2 cloves garlic, minced
10 150 grams fresh spinach

→ Spices

11 Salt and freshly ground black pepper to taste
12 Nutmeg, a pinch (optional)

Guide to Cooking

Step 01

Sauté chicken tenders in a pan over medium heat until fully cooked, then chop into bite-sized pieces.

Step 02

In a saucepan, melt butter and sauté onion and garlic until translucent. Add spinach and cook until wilted. Stir in milk, cream, and Parmesan, seasoning with salt, pepper, and nutmeg. Simmer until sauce slightly thickens.

Step 03

In a baking dish, alternate layers of lasagna sheets, spinach Alfredo sauce, chopped chicken, and mozzarella cheese, finishing with a layer of sauce topped with mozzarella.

Step 04

Cover the dish with aluminum foil and bake in a preheated oven at 180°C for 40 minutes. Remove foil and continue baking for an additional 10 minutes to brown the top.

Step 05

Allow the lasagna to rest for 10 minutes before garnishing with additional Parmesan if desired and serving warm.

Extra Suggestions

  1. Resting the layered dish before serving helps the lasagna set, resulting in cleaner slices.

Necessary Equipment

  • Oven
  • Sauté pan
  • Saucepan
  • Baking dish

Allergen Info

Always check ingredient labels for allergens, and talk to a health expert if you’re unsure.
  • Contains dairy and gluten

Nutritional Info (Per Serving)

Nutrition facts are for general information and shouldn’t replace professional health advice.
  • Energy (Calories): 450
  • Fats: 25 g
  • Carbohydrates: 35 g
  • Protein: 30 g